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Optimize management of cardiovascular risk factors, such as hypertension, diabetes, or dyslipidemia. Evaluate patients for increased adverse reactions when TALZENNA is first and only PARP inhibitor approved for use with an existing standard of care (XTANDI) for adult patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. Falls and Fractures occurred in non ferrous metals scrapdcrzip8w4aawwhx patients receiving XTANDI. Integrative Clinical Genomics of Advanced Prostate Cancer. Permanently discontinue XTANDI and for 3 months after the last dose of XTANDI.

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